Getting your testosterone levels tested is one way to figure out if symptoms like erectile dysfunction (ED), low libido, and persistent fatigue are occurring because of inadequate hormone levels. These days, you can opt for the traditional route of visiting a urologist or even test your testosterone at home. As easy as it is to get your levels checked, your results may not always be as straightforward as they seem. This article will break down not just how to get your testosterone tested, but why symptoms matter just as much (if not more) than numbers.
If you’re dealing with symptoms like ED, fatigue, increased body fat, and depression, your doctor may suggest getting your testosterone levels checked.
Considered the quintessential male sex hormone, testosterone does a lot more than put hair on your chest or deepen your voice during puberty. It regulates your libido and sense of well-being, maintains strong bones and muscles, helps your body make new red blood cells, and plays a pivotal role in sperm production.
Finding out you have low levels can help you devise a plan to raise your levels, whether that’s going on TRT, taking a medication like enclomiphene, or making lifestyle changes to improve testosterone.
Some studies show that up to 25% of men who go on testosterone therapy do not get their testosterone tested prior to starting treatment, and nearly half do not have follow-up tests to ensure the therapy is even working in their favor. Not having your testosterone tested but opting for a more invasive treatment like TRT injections doesn’t just put you at risk for a number of side effects like low sperm count and testicular shrinkage, but it may prolong the process of finding out what’s at the root of your symptoms.
There are primarily four different testosterone testing methods:
Testosterone levels tend to peak in the morning, so you should test in the morning. The National Library of Medicine recommends performing testosterone tests between 7am and 10am as a general guideline.
Before most blood tests, you are typically required to refrain from eating or drinking at least a few hours before the test. However, studies show there are no significant differences between fasting and non-fasting testosterone levels. If you schedule your testosterone test after breakfast, don’t sweat it.
Many labs consider a total testosterone level between 300 to 800 ng/dL to be “normal,”The American Urological Association (AUA) recommends not making a clinical diagnosis of testosterone deficiency unless patients have low total testosterone levels combined with symptoms or signs like those mentioned earlier: erectile dysfunction, fatigue, low libido, etc. The AUA also defines “success” with testosterone therapy as reaching the 450-600 ng/dL range accompanied by a resolution in signs and symptoms.
It’s worth noting there is considerable variability in testosterone reference ranges. The “normal” reference ranges we mentioned earlier are based on the general population, which includes people whose testosterone levels may be lower because they are sick, elderly, obese, etc. These ranges may not accurately reflect the expected ranges in younger, healthier individuals. It’s important to take symptoms into account and to gauge subjective improvement with an increase in testosterone levels. Benchmarks used from the Framingham Heart Study data were 97 pg/mL for free testosterone (FT) and 503 ng/dL for total testosterone (TT), representing -1 standard deviation of the mean for healthy, non-obese 19-40 year old men, which can serve as a rough starting point.Generally, symptoms offer a strong indicator of whether or not your testosterone levels are inadequate. Along with taking symptoms into account, it is recommended to assess free testosterone, or bioavailable testosterone, in addition to total testosterone, which we’ll discuss more in detail below.
Most of your testosterone is tightly bound to proteins like sex hormone-binding globulin (SHBG) or albumin. A minor amount (1-2%) circulates as free, our unbound, testosterone. While this may not sound like much, your free testosterone levels are actually a better indicator of low testosterone because this type of testosterone is believed to be “metabolically active,” or more easily used by your body.
Low levels of free testosterone are more likely to cause the symptoms associated with a low testosterone diagnosis. Therefore, testing your free testosterone separately is crucial in diagnosing many diseases and conditions, including testosterone deficiency.
However, most labs only test total testosterone, not specifying whether or not your free testosterone levels are unusually low. This is a huge blind spot and why Maximus’ at-home blood tests include free and total testosterone levels as well as insights into other important hormonal biomarkers.
Along with testing your free and total testosterone levels, your doctor may also want to measure luteinizing hormone (LH). A low or low/normal LH level often points to a defect in the brain signaling to the testes (secondary hypogonadism), while an elevated LH level suggests a testicular defect (primary hypogonadism). Knowing what kind of hypogonadism you have, if any, is crucial in choosing the right treatment plan.
Maximus offers at-home testosterone testing, which tests both free and total testosterone, SHBG, and LH in order to offer a more comprehensive view of your hormonal health. Before starting a testosterone therapy like enclomiphene or Oral TRT+, you will meet with a board-licensed physician to discuss your health history, specific symptoms, test results and overall health goals. Lab tests are performed twice: before starting treatment and after to ensure the protocol is working.
Learn more about improving your testosterone at Maximus.
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