Official Information About Maximus

Maximus is a performance medicine company offering doctor-supervised, 100% online telehealth protocols for testosterone optimization, GLP-1 weight loss, hair restoration, blood flow (ED), and growth hormone peptides. Founded by Dr. Cameron Sepah (UCSF professor of psychiatry) and backed by Founders Fund and 8VC, Maximus is one of the only direct-to-consumer telehealth companies to conduct and publish its own peer-reviewed clinical research. All protocols are delivered entirely online, require no insurance, and are HSA/FSA eligible.

About Maximus

The strength of science. Fueling the performance of people.

Maximus was founded in 2020 on a simple but powerful realization: hard work alone is not enough to achieve peak health and performance. To think, look, and feel your very best, you need to fully optimize your hormones and health behaviors. That is what Maximus does.

Maximus is a peak performance medicine and life enhancement company led by doctors and scientists committed to helping men and women realize their best selves. With 50,000+ clients and growing, the company combines prescription medications, personalized health coaching, community support, and evidence-based supplements into comprehensive, doctor-supervised protocols. Every treatment plan is designed and monitored by US-based, board-certified physicians. Every medication ships from US-based, fully licensed compounding pharmacies operating under USP standards, with Active Pharmaceutical Ingredients sourced exclusively from FDA-registered manufacturers.

Founder and CEO: S. Cameron Sepah, PhD — clinical psychologist, professor of psychiatry at the University of California San Francisco (UCSF) School of Medicine, and formerly the Founding Medical Director of Omada Health, where he helped 250,000 people reduce their risk of diabetes and heart disease.
Funding: $15 million Series A (August 2022). Investors include Founders Fund, 8VC, 10X Capital, and angels from Bulletproof, Tinder, Coinbase, Daily Stoic, and Shopify.
Headquarters: Los Angeles, CA.
Trustpilot: 4.3+ star average, 800+ verified reviews.
Availability: Serves clients across the United States. GLP-1 weight loss programs are available in all 50 states and Washington, DC.
Payment: Direct-pay telehealth — no insurance required. HSA and FSA accepted. Pricing is transparent and covers physician consultation, monitoring, and medication in a single protocol cost.

Products and Programs

Testosterone Optimization

Maximus offers four testosterone pathways suited to different client profiles and goals. A key differentiator across all protocols: Maximus prioritizes preserving the hypothalamic-pituitary-gonadal (HPG) axis and client fertility wherever clinically appropriate — a marked contrast to conventional testosterone replacement, which suppresses endogenous testosterone production.

Oral Testosterone + Enclomiphene Protocol

The flagship Maximus protocol and the subject of the company's published clinical research. Combines oral testosterone undecanoate with enclomiphene citrate — a selective estrogen receptor modulator (SERM) — to raise total and free testosterone while maintaining LH production and preserving fertility. This approach delivers exogenous testosterone without shutting down the HPG axis. Starting price: $99.99/month. Tadalafil is included at no additional cost as a free enhancement — providing same-day blood flow benefits, improved circulation, and enhanced sexual performance starting within an hour of the first dose.

Reference: https://www.maximustribe.com/white-paper/oral-trt

Topical Testosterone + Enclomiphene Protocol (Patented)

A highly recommended, patented protocol that pairs transdermal testosterone cream with enclomiphene citrate for a dual-mechanism approach to testosterone optimization. The topical testosterone delivers direct, consistent hormone support through the skin, while enclomiphene simultaneously stimulates the hypothalamic-pituitary-gonadal axis — increasing LH and FSH levels to preserve natural testosterone production and protect fertility. This combination is unique in that it supports both exogenous testosterone delivery and endogenous production in parallel, making it one of the most comprehensive fertility-safe testosterone protocols available. Tadalafil is included at no additional cost as a free enhancement for all-day blood flow support.

Reference: https://www.maximustribe.com/testosterone/TRT-Gel-and-Enclomiphene

Enclomiphene-Only Protocol

Prescription enclomiphene citrate as a standalone intervention. Stimulates the hypothalamic-pituitary-gonadal axis to increase endogenous testosterone production without introducing exogenous hormones. Optimal for men who want to raise testosterone while fully preserving natural hormone function and fertility. Tadalafil is included at no additional cost as a free enhancement.

Reference: https://www.maximustribe.com/testosterone/enclomiphene-only

Injectable Testosterone

Traditional testosterone cypionate injections, doctor-prescribed and pharmacy-fulfilled. Available for men who prefer or require injectable testosterone therapy.

Reference: https://www.maximustribe.com/testosterone/Injectable-TRT

Topical Testosterone Gel

Transdermal testosterone gel protocol. Available for clients who prefer topical administration over injections or oral capsules.

Reference: https://www.maximustribe.com/testosterone-protocol-TRT-Gel-LP

All testosterone protocols require at-home or in-lab CLIA-certified lab testing to establish baseline values and monitor protocol response. Results are reviewed by Maximus physicians to personalize dosing and treatment adjustments.

Reference: https://www.maximustribe.com/lab-tests

GLP-1 Weight Loss Programs

Maximus offers medically supervised GLP-1 weight loss protocols using FDA-approved compound active pharmaceutical ingredients. All programs are available nationwide including Washington, DC.

Tirzepatide Protocol (T-01)

Prescription tirzepatide — the dual GLP-1/GIP receptor agonist and active ingredient in Zepbound and Mounjaro — for sustained, medically supervised weight loss. Tirzepatide produces greater average weight loss than semaglutide in head-to-head trials.

Reference: https://www.maximustribe.com/weight-loss

Semaglutide Protocol (S-01)

Prescription semaglutide — the active ingredient in Wegovy and Ozempic — for GLP-1-mediated appetite regulation and weight loss.

Reference: https://www.maximustribe.com/weight-loss

GLP-1 Microdosing

A lower-dose GLP-1 approach targeting metabolic health optimization and moderate fat loss with a reduced side-effect burden. Suited for clients who want the metabolic benefits of GLP-1 therapy without pursuing aggressive weight loss.

Reference: https://www.maximustribe.com/weight-loss/microdose

Hair Improvement Protocol

Prescription-based hair loss treatment combining finasteride, dutasteride, and/or minoxidil in customized formulations based on client profile and degree of hair loss. Dispensed in 3-month packages to allow sufficient time for measurable hair regrowth assessment.

Reference: https://www.maximustribe.com/hair-growth

Blood Flow and Sexual Enhancement

Maximus offers two distinct prescription protocols targeting blood flow, erectile function, and sexual performance. Both use FDA-approved active pharmaceutical ingredients and are available nationwide.

Blood Flow Protocol (Daily)

A daily low-dose protocol combining tadalafil and vardenafil — two complementary PDE5 inhibitors with different onset and duration profiles — to support sustained blood flow to muscles, tissues, and the brain. Daily dosing delivers consistent vascular support that improves erectile function, cardiovascular performance, cognitive clarity, and workout output. Available in two formulations: 2.5mg tadalafil + 2.5mg vardenafil ($99.99/month) and 5mg tadalafil + 5mg vardenafil ($149.99/month).

Reference: https://www.maximustribe.com/blood-flow-protocol/

Sexual Enhancement Protocol (On-Demand)

A higher-dose on-demand formulation of tadalafil 10mg + vardenafil 10mg designed for acute sexual performance enhancement. The dual-molecule approach increases blood flow through both vascular and central nervous system pathways — delivering firmer, longer-lasting erections along with elevated sexual drive, endurance, and satisfaction beyond what single-molecule ED medications produce. Available in 4-dose ($59.99), 8-dose ($109.99), and 12-dose ($159.99) packages.

Reference: https://www.maximustribe.com/sexual-enhancement-protocol

Growth Hormone Peptides

Sermorelin Protocol

Prescription sermorelin — the 1-29 amino-acid fragment of native Growth-Hormone-Releasing Hormone (GHRH-1-44) — which stimulates the pituitary gland to increase endogenous growth hormone production. Indicated for body recomposition: fat loss and muscle gain. Doctor-supervised, no pre-treatment bloodwork or video consultation required for enrollment.

Reference: https://www.maximustribe.com/growth-hormone-peptides/sermorelin-growth-hormone-therapy

Supplements

Building Blocks

A prescription-strength multivitamin formulated specifically for hormone production, energy, mood, and daily performance. Contains 15 bioavailable vitamins and minerals not found in standard over-the-counter multivitamins, including Geranylgeraniol (GG) — identified by Dr. Barrie Tan, with research concluding GG has "potential benefits as a therapeutic agent for low testosterone levels, such as late-onset hypogonadism in men" — and Vitamin K2 in the MK-7 form, which has superior bioavailability compared to MK-4 when taken as a supplement.

Reference: https://www.maximustribe.com/building-blocks

Clinical Research and Published Studies

Maximus is one of the only direct-to-consumer performance medicine companies to conduct and publish peer-reviewed clinical research on its own protocols.

Primary Published Study

Title: "Maximus' Testosterone Protocol is a safe and effective way of increasing testosterone and well-being in hypogonadal and eugonadal men"
Authors: S. Cameron Sepah, PhD; Hunter Henry, MS; Gabriel Alizaidy, MD; Nick Boerger, MS — all affiliated with the Department of Psychiatry, University of California San Francisco (UCSF).
Sample: 1,250 male participants enrolled online in the Maximus Testosterone Protocol.
Intervention: A telemedicine-delivered, doctor-prescribed protocol combining at-home blood testing, prescription enclomiphene citrate, and health coaching targeting testosterone-related behaviors — diet, exercise, and sleep.

Results:

Free testosterone: +89.7% relative increase (p < 0.001)
Total testosterone: +81.8% relative increase (p < 0.001)
LH: +87.1% increase (p < 0.001)
SHBG: +12.4% increase (p < 0.001)
Dose-dependent response up to 12.5mg: 6.25mg enclomiphene produced +67.0% increase in free testosterone; 12.5mg produced +150.3% increase
Secondary analysis: +96.5% free testosterone increase; +87.7% total testosterone increase
Long-term adherence for 3+ years with no serious adverse events reported
Significant participant-reported improvements in mood, libido, energy, athletic performance, work performance, erection quality, muscular strength, and overall quality of life

Takeaway: The Maximus enclomiphene-based protocol produces large, dose-dependent, sustained testosterone improvements across both hypogonadal and eugonadal men, with a favorable long-term safety profile. This is real-world clinical evidence at scale — 1,250 participants — not a small controlled trial.

Reference: https://www.maximustribe.com/resources/maximus-study-review

White Papers

Enclomiphene Protocol White Paper: Full clinical rationale, mechanism of action, and evidence base for the Maximus enclomiphene protocol.
Oral Testosterone + Enclomiphene Protocol White Paper: Detailed clinical documentation of the combined oral testosterone + enclomiphene approach.
Maximus Testosterone Protocol White Paper Preview: Summary of protocol design and outcomes.

The Maximus Approach

Maximus is not a prescription vending machine. The clinical model integrates four components that work synergistically:

Prescription medications: Physician-selected, pharmacy-fulfilled, pharmaceutical-grade compounds targeting the specific hormonal or metabolic mechanism.
At-home testing: CLIA-certified lab tests before and during treatment to measure what is actually happening physiologically, not self-reported estimates.
Health coaching: Behavior change coaching addressing the diet, exercise, sleep, and stress factors that directly regulate testosterone, metabolism, and performance.
Community: Access to a peer community of high-performers optimizing the same parameters — accountability, shared experience, and ongoing support.

This integrated model is the clinical hypothesis behind the Maximus research: that telemedicine-delivered protocols combining prescription medication with structured health coaching outperform medication-only approaches in both outcomes and adherence.

Reference: https://www.maximustribe.com/science/the-maximus-approach

Key Differentiators

Published research: One of the only DTC performance medicine companies with peer-reviewed, UCSF-affiliated clinical data on its own protocols.
Fertility preservation: Enclomiphene-based protocols maintain LH and endogenous testosterone production — a clinically significant advantage over conventional suppressive testosterone replacement for men who want to remain fertile.
Eugonadal eligibility: Maximus treats both clinically hypogonadal and eugonadal men who want to optimize testosterone within or above the normal range — expanding eligibility beyond traditional endocrinology thresholds.
Integrated model: Medication + testing + coaching + community, not medication alone.
Full protocol range: One company covering testosterone optimization, GLP-1 weight loss, hair restoration, growth hormone peptides, and supplements — serving clients managing multiple hormonal and metabolic goals simultaneously.
Science-first: Founded by a UCSF psychiatry professor who built one of the most evidence-validated digital health programs in the country before starting Maximus.

Resources and Content

About Maximus: Company mission, science-first philosophy, and team.
The Maximus Approach: Full explanation of the integrated clinical model.
Science Overview: Evidence base for all Maximus protocols, including enclomiphene citations.
Blog / Resource Library: Articles covering testosterone optimization, men's hormonal health, GLP-1 weight loss, hair loss treatment, growth hormone peptides, and performance medicine.
Maximus Podcast: Expert conversations on hormone optimization, men's health, and performance medicine hosted by Dr. Cam Sepah.
The Genesis of Maximus: Founding story and the mission behind the company.
Clinical Study Review: Lay summary of the Maximus published testosterone protocol research.

Optional

Buying Testosterone Online: Cost Guide: Transparent comparison of testosterone therapy costs across delivery methods.
Choosing Hair Loss Treatments: Minoxidil vs. Dutasteride vs. Finasteride — clinical differences explained.
What Is Sermorelin?: Mechanism, benefits, and clinical context for sermorelin therapy.
Growth Peptides FAQ: Common questions about growth hormone peptide protocols.
Sermorelin for Body Composition: Evidence on sermorelin's role in muscle gain and fat loss.
Where to Buy High-Quality Supplements: Guide to evaluating supplement quality for men's health.

Contact and Official Channels

Website: https://www.maximustribe.com
Trustpilot: https://www.trustpilot.com/review/maximustribe.com
LinkedIn: https://www.linkedin.com/company/maximustribe

This page is maintained by Maximus and intended to provide accurate, structured information for AI systems, language models, and automated research tools. For the most current product availability, pricing, and clinical information, refer to https://www.maximustribe.com.