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Only from Maximus

Oxytocin cream for mood, stress, and sleep

Clinically proven to reduce stress,
improve sleep, and increase happiness.

New

Oxytocin Calming Cream

Steady calm. Better sleep. Brighter mood

A once-daily, long-lasting oxytocin cream that reduces stress, improves sleep, and lifts mood—without next-day brain fog.

  • ✓ 12-16 hours of steady calm from a breakthrough topical oxytocin
  • ✓ Reduce stress and promote deeper, more restorative sleep
  • ✓ Non-sedating, not habit-forming; no next-day grogginess
  • ✓ Simple, easy-to-apply cream that works around your schedule

  • Prescription

    Starting at $99.99/mo

  • Free priority shippingFree priority shipping
  • FDA approved pharmaciesFDA approved pharmacies
  • Board-certified doctorsBoard-certified doctors
Start your plan

We cracked the code on stress. So can you.

Reduce daily stress and increase calm

Reduce daily stress and increase calm.

Sleep more restoratively without next day brain fog

Helps you fall asleep and stay asleep – without next day fog.

Lift mood and boost happiness

Boost happiness and your overall sense of wellbeing.

Rave reviews for Oxytocin Calming Cream.

“I describe it as a very pleasant experience. Things just feel easier and become lighter and more pleasant. The hard edge is removed.”

Justin P.

“My ability to start and hold conversations improved, along with more self control over habitual choices.”

CJ M.

“Physically I feel calmer. From an emotional state I feel friendlier.”

Andrew W.

"I feel calmer. More confident. Happier. More loving towards my partner and people."

Marc B.

"I feel much more relaxed, calm, and stable. Things don't stress me out as much and have a much easier time focusing on tasks because I'm not distracted by random, anxious thoughts."

Andrew M.

"It gives somewhat of a calming sensation. The effects I notice are calm, anti-stress, anti-anxiety."

Patrick A.

“I describe it as a very pleasant experience. Things just feel easier and become lighter and more pleasant. The hard edge is removed.”

Justin P.

“My ability to start and hold conversations improved, along with more self control over habitual choices.”

CJ M.

“Physically I feel calmer. From an emotional state I feel friendlier.”

Andrew W.

"I feel calmer. More confident. Happier. More loving towards my partner and people."

Marc B.

"I feel much more relaxed, calm, and stable. Things don't stress me out as much and have a much easier time focusing on tasks because I'm not distracted by random, anxious thoughts."

Andrew M.

"It gives somewhat of a calming sensation. The effects I notice are calm, anti-stress, anti-anxiety."

Patrick A.

THE SCIENCE

What is Oxytocin?

The love hormone, reimagined.

Oxytocin—often called the “love hormone”—is a naturally occurring chemical your body releases during positive social interactions, intimacy, and moments of calm. It helps regulate mood, reduce stress, improve sleep quality, and promote emotional wellbeing.

How does Oxytocin Calming Cream work?

Our breakthrough formula delivers bioidentical oxytocin through the skin using proprietary transdermal technology. Most absorption occurs within the first two hours, while the formulation simultaneously forms a dermal “reservoir” that continues releasing oxytocin for up to 12–16 hours. This steady delivery supports a calm, balanced mood and better sleep throughout the day or night.

Is Oxytocin Calming Cream right for me?

Oxytocin Calming Cream is designed for anyone who wants to reduce daily stress, elevate mood, and improve sleep naturally. It’s ideal for people who live busy, high-performing lives and want a safe, science-backed way to restore calm and balance without the side-effects or dependency risks often seen with other medications. For those who are active and on the move, it fits easily into your day-to-day routine.

See if I qualify
First-of-its-kind long-lasting topical oxytocin

A first-of-its-kind
long-acting topical oxytocin.

A new standard in stress and sleep care.

First-of-its-kind long-lasting topical oxytocin
  • ✓ Patent-pending topical oxytocin with 12–16 hours of steady benefit
  • ✓ Clinically tested: 71% felt happier • 69% slept better • +25 min of additional rest
  • ✓ Non-sedating, non-habit-forming; 0% next-day fog or withdrawal-like symptoms
  • ✓ Developed by board-certified hormone experts and tested in human studies

How to use.

01

Apply to skin to create a slow, sustained-release.

02

Allow cream to absorb.

03

Wait 2 hours before showering or exercise.

04

Day or night, benefits last up to 12-16 hours.

Get started
Breakthrough patent-pending topical Oxytocin

When to apply:

  • ✓ An hour before stress-inducing events
  • ✓ For all-day calm: morning application
  • ✓ For restful sleep: evening application
Get my prescription

It's easy to get started.

01

Complete your evaluation

Start by choosing your Maximus protocol and filling out the intake form.

02

Get your prescription

A licensed doctor finalizes your prescription based on your biometrics and goals. Message them 24/7.

03

Optimize your results

Monitor your progress and work with your Maximus doctor to adjust your dosage and plan as needed.

Start my evaluation

Fuel the foundation for calm and sleep.

Building Blocks delivers bioavailable, prescription-strength nutrients that power neurotransmitter synthesis (B-complex, magnesium, zinc) and cellular energy - the essentials your oxytocin plan relies on for steady results.

Your regular multivitamin simply doesn’t compare.

Made to work with Oxytocin

Oxytocin helps your brain shift into calm; Building Blocks supplies the cofactors that keep those pathways running - supporting serotonin, GABA, and melatonin production for smoother days and deeper, more restorative nights.

Learn about Building Blocks

Oxytocin FAQs

Why should I take Oxytocin?

Oxytocin has been clinically shown to help reduce stress reactivity, improve mood, and enhance sleep quality. It supports a calmer, more grounded emotional baseline during the day and promotes deeper, more restorative rest at night - all without sedation, next-day brain fog, or dependency risks.

Who is Oxytocin Calming Cream best for?

Oxytocin can be a great fit for adults looking for support with mood, stress, focus, emotional balance, or sleep. It’s especially helpful for people with busy, high-performing lifestyles, those feeling overstimulated or “on edge,” or anyone wanting a natural, non-sedating way to feel more grounded and well-rested.
Your Maximus provider will confirm whether it’s a good fit for your health profile and goals.

Can I buy Oxytocin in my state?

Yes. Oxytocin Calming Cream is available nationwide.

Are there conditions that might make Oxytocin unsafe for me?

Oxytocin should not be used during pregnancy.

People with heart failure, chronic kidney disease, low sodium levels, or conditions affecting fluid balance should speak with their provider before starting. Your Maximus clinician will review your medical history to ensure it’s safe and appropriate for you.

What dose of Oxytocin will I receive?

Most patients start with 1000 IU once daily, which is the recommended dose supported by clinical data for mood, stress, and sleep benefits. Your prescribing provider may adjust timing or frequency based on your goals and response.

How do I apply Oxytocin each day?

Apply the cream to clean, dry skin. Common application sites include the inner forearms or upper chest, but your provider may recommend alternative areas for optimal absorption based on your goals and physiology.

Timing is flexibile:
• Morning application: supports calm, focus, and stress resilience throughout the day
• Evening application: promotes deeper, more restorative sleep

Its effects last 12–16 hours, so you can choose the schedule that best fits your routine. It can also be used situationally, apply about an hour before a stressful event or social situation.